The Bewildering Antitubercular Action of Pyrazinamide.

Abstract excerpt

Pyrazinamide (PZA) is a cornerstone antimicrobial drug used exclusively for the treatment of tuberculosis (TB). Due to its ability to shorten drug therapy by 3 months and reduce disease relapse rates, PZA is considered an irreplaceable component of standard first-line short-course therapy for drug-susceptible TB and second-line treatment regimens for multidrug-resistant TB. Despite over 60 years of research on...

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• Antitubercular Agents
• Clinical Trials as Topic
• Drug Development
• Drug Resistance, Multiple, Bacterial
• Mice