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Article

Murine Gut Microbiome Association With APOE Alleles.

Frontiers in immunology - 1 Jan 2020

Parikh Ishita J, Estus Janice L, Zajac Diana J, Malik Manasi, Maldonado Weng Juan, Tai Leon M, Chlipala George E, LaDu Mary Jo, Green Stefan J, Estus Steven

Abstract excerpt

Background: Since APOE alleles represent the most impactful genetic risk factors for Alzheimer's disease (AD), their differential mechanism(s) of action are under intense scrutiny. APOE4 is robustly associated with increased AD risk compared to the neutral APOE3 and protective APOE2. APOE alleles have also been associated with differential inflammation and gastrointestinal recovery after insult in human and...

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Identifiers

PMID: 32117315
DOI: 10.3389/fimmu.2020.00200
PMCID: PMC7034241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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