Article

Predicting neurodegenerative disease using pre-pathology gut microbiota composition: a longitudinal study in mice modeling Alzheimer’s disease pathologies

2022-04-12

Abstract excerpt

The gut microbiota-brain axis is suspected to contribute to the development of Alzheimer’s Disease (AD), a neurodegenerative disease characterized by amyloid-β plaque deposition, neurofibrillary tangles, and neuroinflammation. To evaluate the role of the gut microbiota-brain axis in AD, we characterized the gut microbiota of 3xTg-AD mice modeling amyloidosis and tauopathy and wild type (WT) genetic controls. Fecal...

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Literature Corpus work: 560acf92-cf3f-5ddc-8ec5-ea415232b37d
DOI: 10.21203/rs.3.rs-1538737/v1

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