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Article

APOE genetics influence murine gut microbiome.

Scientific reports - 3 Feb 2022

Zajac Diana J, Green Stefan J, Johnson Lance A, Estus Steven

Abstract excerpt

Apolipoprotein E (APOE) alleles impact pathogenesis and risk for multiple human diseases, making them primary targets for disease treatment and prevention. Previously, we and others reported an association between APOE alleles and the gut microbiome. Here, we evaluated effects of APOE heterozygosity and tested whether these overall results extended to mice maintained under ideal conditions for microbiome...

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Identifiers

PMID: 35115575
DOI: 10.1038/s41598-022-05763-1
PMCID: PMC8814305

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