Article

Genetic correlations between gut microbiome genera, Alzheimer’s disease diagnosis, and APOE genotypes: a polygenic risk score study

2022-12-05

Abstract excerpt

<h4>Background: </h4> A growing body of evidence suggests that dysbiosis of the human gut microbiota is associated with neurodegenerative diseases like Alzheimer’s disease (AD) via neuroinflammatory processes across the microbiota-gut-brain axis (MGBA). The gut microbiota affects brain health through the secretion of toxins and short-chain fatty acids, which modulates gut permeability and numerous immune functions...

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Literature Corpus work: d8cb42fb-25e2-5617-be06-ca1e2774245b
DOI: 10.21203/rs.3.rs-2292371/v1

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