Article
Impact of Vitamin D Binding Protein Levels on Alzheimer's Disease: A Mendelian Randomization Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Zhang Haihua, Wang Tao, Han Zhifa, Wang Longcai, Zhang Yan, Wang Lijun, Liu Guiyou
Abstract excerpt
Until now, observational studies, randomized controlled trials (RCTs), and Mendelian randomization (MR) studies have explored the impact of vitamin D on Alzheimer's disease (AD), and reported inconsistent findings. In MR studies, the sensitivity analysis by removing GC rs2282679 variant highlighted no association of 25OHD levels with AD risk, which indicates that vitamin D-binding protein (DBP) encoded by GC may...
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