Article
The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study.
PLoS medicine - 1 Oct 2014
Leong Aaron, Rehman Waheed, Dastani Zari, Greenwood Celia, Timpson Nicholas, Langsetmo Lisa, Berger Claudie, Fu Lei, Wong Betty Y L, Malik Suneil, Malik Rainer, Hanley David A, Cole David E C, Goltzman David, Richards J Brent
Abstract excerpt
BACKGROUND: Observational studies have shown that vitamin D binding protein (DBP) levels, a key determinant of 25-hydroxy-vitamin D (25OHD) levels, and 25OHD levels themselves both associate with risk of disease. If 25OHD levels have a causal influence on disease, and DBP lies in this causal path...
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