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Article

Glucose homeostasis is impaired in mice deficient in the neuropeptide 26RFa (QRFP).

BMJ open diabetes research & care - 1 Feb 2020

El-Mehdi Mouna, Takhlidjt Saloua, Khiar Fayrouz, Prévost Gaëtan, do Rego Jean-Luc, do Rego Jean-Claude, Benani Alexandre, Nedelec Emmanuelle, Godefroy David, Arabo Aranaud, Lefranc Benjamin, Leprince Jérôme, Anouar Youssef, Chartrel Nicolas, Picot Marie

Abstract excerpt

INTRODUCTION: 26RFa (pyroglutamyl RFamide peptide (QRFP)) is a biologically active peptide that has been found to control feeding behavior by stimulating food intake, and to regulate glucose homeostasis by acting as an incretin. The aim of the present study was thus to investigate the impact of 26RFa gene knockout on the regulation of energy and glucose metabolism. RESEARCH DESIGN AND METHODS: 26RFa mutant mice...

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Identifiers

PMID: 32114486
DOI: 10.1136/bmjdrc-2019-000942
PMCID: PMC7050347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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