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Article

Pep19 Has a Positive Effect on Insulin Sensitivity and Ameliorates Both Hepatic and Adipose Tissue Phenotype of Diet-Induced Obese Mice.

International journal of molecular sciences - 7 Apr 2022

Silvério Renata, Barth Robson, Heimann Andrea S, Reckziegel Patrícia, Dos Santos Gustavo J, Romero-Zerbo Silvana Y, Bermúdez-Silva Francisco J, Rafacho Alex, Ferro Emer S

Abstract excerpt

Peptide DIIADDEPLT (Pep19) has been previously suggested to improve metabolic parameters, without adverse central nervous system effects, in a murine model of diet-induced obesity. Here, we aimed to further evaluate whether Pep19 oral administration has anti-obesogenic effects, in a well-established high-fat diet-induced obesity model. Male Swiss mice, fed either a standard diet (SD) or high-fat diet (HFD), were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35456900
DOI: 10.3390/ijms23084082
PMCID: PMC9030859

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