Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A model for obesity and gigantism due to disruption of the Ankrd26 gene.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2008

Bera Tapan K, Liu Xiu-Fen, Yamada Masanori, Gavrilova Oksana, Mezey Eva, Tessarollo Lino, Anver Miriam, Hahn Yoonsoo, Lee Byungkook, Pastan Ira

Abstract excerpt

Obesity is a major health hazard that is caused by a combination of genetic and behavioral factors. Several models of obesity have been described in mice that have defects in the production of peptide hormones, in the function of cell membrane receptors, or in a transcription factor required for neuronal cell development. We have been investigating the function of a family of genes (POTE and ANKRD26) that encode...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Size
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Expressed Sequence Tags

Share to Gigantism

Share to Homozygote

Share to Insulin Resistance

Share to Intercellular Signaling Peptides and Proteins

Share to Obesity

Source

Open in PubMed Open full text

Identifiers

PMID: 18162531
DOI: 10.1073/pnas.0710978105
PMCID: PMC2224199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A model for obesity and gigantism due to disruption of the Ankrd26 gene.PMID 18162531Read ↗

The muscle ankyrin repeat proteins CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to pressure overload.Semantic proximity Read ↗

Glucose homeostasis is impaired in mice deficient for the neuropeptide 26RFa (QRFP)Semantic proximity Read ↗

Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalitiesSemantic proximity Read ↗

Expression of ankyrin repeat and suppressor of cytokine signaling box protein 4 (Asb-4) in proopiomelanocortin neurons of the arcuate nucleus of mice produces a hyperphagic, lean phenotype.Semantic proximity Read ↗

Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha.Semantic proximity Read ↗

Mice heterozygous for Atp10c, a putative amphipath, represent a novel model of obesity and type 2 diabetes.Semantic proximity Read ↗

Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations.Semantic proximity Read ↗

Angiotensin receptor-binding protein ATRAP/Agtrap inhibits metabolic dysfunction with visceral obesity.Semantic proximity Read ↗

Molecular and phenotypic analysis of Attractin mutant mice.Semantic proximity Read ↗

Torso-Like Is a Component of the Hemolymph and Regulates the Insulin Signaling Pathway in Drosophila.Semantic proximity Read ↗

Control of triglyceride storage by a WD40/TPR-domain protein.Semantic proximity Read ↗

The Role of ANK in Calcium Pyrophosphate Deposition Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.