Article
Genetic variants in class II transactivator are associated with chronic hepatitis B virus infection in the Han Chinese population.
International journal of immunogenetics - 1 Oct 2020
Su Mingkuan, Chen Zongyun, Zheng Jinli, Chen Yong
Abstract excerpt
Class II transactivator (CIITA) is a master regulator of MHC gene expression and plays a role in inducing the expression of other immune system genes, including IL-4, IL-10 and Fas ligand, as well as more than 60 other immunologically significant genes. We used CIITA as a candidate gene to analyse whether any single-nucleotide polymorphisms (SNPs) are associated with chronic hepatitis B virus (HBV) infection. In...
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