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Article

Functional Polymorphisms in IRAKs Are Related to Hepatocellular Carcinoma Risk in Chinese Population.

BioMed research international - 1 Jan 2018

Wang Hui, Song Ci, Qi Qi, Huang Tongtong, Wang Lijuan, Chen Jianguo, Zhu Jian, Hu Zhibin, Dai Juncheng

Abstract excerpt

BACKGROUND: Interleukin 1 receptor associated kinases (IRAKs) play a central role in TLR signaling pathway. Scarce literature has investigated the association of potential functional genetic variants of IRAKs with Hepatitis B Virus- (HBV-) related hepatocellular carcinoma (HCC). METHODS: A case-control study with 1,538 HBV-positive HCC patients and 1,465 chronic HBV carriers was conducted to evaluate the effects...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 30112356
DOI: 10.1155/2018/1252849
PMCID: PMC6077667

Genes

IRAK4

Variants

rs4251545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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