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Article

Strong association of functional polymorphism in IL-12B with susceptibility to chronic hepatitis B in Tunisia.

Journal of medical virology - 1 Aug 2021

Ben Dhifallah Imène, Ayouni Kaouther, Jmel Haifa, Kammoun Wafa, Hamzaoui Kamel, Sadraoui Amel, Triki Henda

Abstract excerpt

BACKGROUND: The chronicity or clearance of hepatitis B virus (HBV) infection depends on viral and genetic variables. The immune response against HBV is thought to be responsible for viral persistence or clearance. Cytokines such as interleukin 1-2B (IL1-2B) involved in the T-helper 1 system are key mediators in the defence mechanisms against viral infection and play a role in the regulation of HBV clearance...

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PMID: 33739474
DOI: 10.1002/jmv.26946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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