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Article

Association of PARP1 polymorphisms with response to chemotherapy in patients with high-risk neuroblastoma.

Journal of cellular and molecular medicine - 1 Apr 2020

Avitabile Marianna, Lasorsa Vito Alessandro, Cantalupo Sueva, Cardinale Antonella, Cimmino Flora, Montella Annalaura, Capasso Dalila, Haupt Riccardo, Amoroso Loredana, Garaventa Alberto, Quattrone Alessandro, Corrias Maria Valeria, Iolascon Achille, Capasso Mario

Abstract excerpt

The genetic aetiology and the molecular mechanisms that characterize high-risk neuroblastoma are still little understood. The majority of high-risk neuroblastoma patients do not take advantage of current induction therapy. So far, one of the main reasons liable for cancer therapeutic failure is the acquisition of resistance to cytotoxic anticancer drugs, because of the DNA repair system of tumour cells. PARP1 is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32103589
DOI: 10.1111/jcmm.15058
PMCID: PMC7171401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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