Article
MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients.
International journal of molecular sciences - 14 Apr 2020
Olivera Gladys G, Yáñez Yania, Gargallo Pablo, Sendra Luis, Aliño Salvador F, Segura Vanessa, Sanz Miguel Ángel, Cañete Adela, Castel Victoria, Font De Mora Jaime, Hervás David, Berlanga Pablo, Herrero María José
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in Pharmacogenetics can play an important role in the outcomes of the chemotherapy treatment in Neuroblastoma, helping doctors maximize efficacy and minimize toxicity. Employing AgenaBioscience MassArray, 96 SNPs were genotyped in 95 patients looking for associations of SNP with response to induction therapy (RIT) and grade 3-4 toxicities, in High Risk patients. Associations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
