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The Study on the Expression Level of PARP-1 in Glioma and Computational Screening of PARP-1 Inhibitors

2022-06-17

Abstract excerpt

<title>Abstract</title> <p>Gliomas are the most common primary intracranial malignancies. Current standard treatments include surgical resection, supplemented by radiotherapy and chemotherapy, but the prognosis is poor. PARP-1 (Poly ADP-ribose polymerase 1) inhibitors have become a hotspot in cancer treatment by affecting DNA damage repair pathways, such as metastatic breast cancer, advanced prostate cancer, ovar...

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Literature Corpus work
411b50a2-867d-5952-bf09-e7e9849ee7cc
DOI
10.21203/rs.3.rs-1714523/v1
Open publication

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