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Article

Polymorphisms in poly (ADP-ribose) polymerase-1 (PARP1) promoter and 3' untranslated region and their association with PARP1 expression in breast cancer patients.

International journal of clinical and experimental pathology - 1 Jan 2015

Zhai Lili, Li Shuai, Li Huilan, Zheng Yi, Lang Ronggang, Fan Yu, Gu Feng, Guo Xiaojing, Zhang Xinmin, Fu Li

Abstract excerpt

Within the past several years, inhibition of the PARP1 activity has been emerged as one of the most exciting and promising strategies for triple-negative breast cancer (TNBC) therapy. The purpose of this study is to assess PARP1 expression in TNBCs and to evaluate the association between polymorphisms in PARP1 promoter or 3' untranslated region (3'UTR) and PARP1 expression. It was found that PARP1 was...

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Identifiers

PMID: 26261599
PMCID: PMC4525933

Genes

PARP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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