Article
Analysis of DNA repair gene polymorphisms and survival in low-grade and anaplastic gliomas.
Journal of neuro-oncology - 1 Dec 2011
Berntsson Shala Ghaderi, Wibom Carl, Sjöström Sara, Henriksson Roger, Brännström Thomas, Broholm Helle, Johansson Christoffer, Fleming Sarah J, McKinney Patricia A, Bethke Lara, Houlston Richard, Smits Anja, Andersson Ulrika, Melin Beatrice S
Abstract excerpt
The purpose of this study was to explore the variation in DNA repair genes in adults with WHO grade II and III gliomas and their relationship to patient survival. We analysed a total of 1,458 tagging single-nucleotide polymorphisms (SNPs) that were selected to cover DNA repair genes, in 81 grade II and grade III gliomas samples, collected in Sweden and Denmark. The statistically significant genetic variants from...
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