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Germline Variants in DNA Repair Genes and Susceptibility to Pediatric Peripheral Neuroblastic Tumors: A Case-Controle Study

2026-04-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Peripheral neuroblastic tumors (PNTs) are embryonal pediatric neoplasms characterized by marked clinical heterogeneity. Germline variation in DNA repair genes may influence genomic stability and modulate tumor susceptibility and disease phenotype. We evaluated the association of single nucleotide variants (SNVs) in <italic>PARP1</italic> (rs1136410), <ital...

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Literature Corpus work
b3da047f-cdfd-577c-bf89-45830c47bb7f
DOI
10.21203/rs.3.rs-9419277/v1
Open publication

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