Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease

26 Feb 2020

Abstract excerpt

The ex vivo generation of gastrointestinal organoids from crypt stem cells opens up the possibility of new research approaches investigating gastrointestinal diseases. We used this technology to study differences between healthy controls and patients with celiac disease (CD). We noticed distinct dissimilarities in the phenotypes of organoids between our study groups and found considerable variations in their gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease Research and Management
Share to Digestive system and related health
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32103108
DOI: 10.1038/s41598-020-60521-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac diseasePMID 32103108Read ↗

Stem cell-derived intestinal organoids: a novel modality for IBDSemantic proximity Read ↗

Gut organoids: mini-tissues in culture to study intestinal physiology and diseaseSemantic proximity Read ↗

Insights into Modeling Inflammatory Bowel Disease from Stem Cell Derived Intestinal OrganoidsSemantic proximity Read ↗

Generation of human colon organoids from healthy and inflammatory bowel disease mucosaSemantic proximity Read ↗

Drug Discovery via Human-Derived Stem Cell OrganoidsSemantic proximity Read ↗

Ex vivo culture of the intestinal epithelium: strategies and applicationsSemantic proximity Read ↗

Intestinal organoid culture model is a valuable system to study epithelial barrier function in IBDSemantic proximity Read ↗

Advances and applications of gut organoids: modeling intestinal diseases and therapeutic developmentSemantic proximity Read ↗

The Role of Organoids as a Novel Platform for Modeling of Inflammatory Bowel DiseaseSemantic proximity Read ↗

Intestinal organoids: A versatile platform for modeling gastrointestinal diseases and monitoring epigenetic alterationsSemantic proximity Read ↗

Understanding disruption of the gut barrier during inflammation: Should we abandon traditional epithelial cell lines and switch to intestinal organoids?Semantic proximity Read ↗

Patient-derived organoids for therapy personalization in inflammatory bowel diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.