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Article

Intestinal organoid culture model is a valuable system to study epithelial barrier function in IBD

5 Dec 2017

Abstract excerpt

With great interest, we have read the article by Dotti et al ,1 who analysed the transcriptional signature of epithelial organoid cultures (EpOCs) generated from patients with UC and non-IBD controls. They identified a set of genes that were differentially expressed between UC and control EpOCs, among which several were associated with epithelial secretory and antimicrobial defense. The authors further stated...

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PMID: 29208677
DOI: 10.1136/gutjnl-2017-315685

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