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Ex vivo culture of the intestinal epithelium: strategies and applications

19 May 2014

Abstract excerpt

Limited pools of resident adult stem cells are critical effectors of epithelial renewal in the intestine throughout life. Recently, significant progress has been made regarding the isolation and in vitro propagation of fetal and adult intestinal stem cells in mammals. It is now possible to generate ever-expanding, three-dimensional epithelial structures in culture that closely parallel the in vivo epithelium of...

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PMID: 24841573
DOI: 10.1136/gutjnl-2014-307204

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