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Article

The Role of Organoids as a Novel Platform for Modeling of Inflammatory Bowel Disease

17 Feb 2021

Abstract excerpt

Inflammatory bowel disease (IBD) is a chronic relapsing-remitting immune-mediated disorder affecting the gut. It is common in Westernized regions and is increasing in incidence in developing countries. At a molecular level, intrinsic deficiencies in epithelial integrity, mucosal barrier function, and mechanisms of immune response and resolution contribute to the development of IBD. Traditionally two platforms...

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PMID: 33681101
DOI: 10.3389/fped.2021.624045

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