Article
Molecular Epidemiology of P. vivax in Iran: High Diversity and Complex Sub-Structure Using Neutral Markers, but No Evidence of Y976F Mutation at pvmdr1.
PloS one - 1 Jan 2016
Hamedi Yaghoob, Sharifi-Sarasiabi Khojasteh, Dehghan Farzaneh, Safari Reza, To Sheren, Handayuni Irene, Trimarsanto Hidayat, Price Ric N, Auburn Sarah
Abstract excerpt
BACKGROUND: Malaria remains endemic at low levels in the south-eastern provinces of Iran bordering Afghanistan and Pakistan, with the majority of cases attributable to P. vivax. The national guidelines recommend chloroquine (CQ) as blood-stage treatment for uncomplicated P. vivax, but the large influx of imported cases enhances the risk of introducing CQ resistance (CQR). METHODOLOGY AND PRINCIPAL FINDINGS: The...
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