Article
FKBP5-associated miRNA signature as a putative biomarker for PTSD in recently traumatized individuals.
Scientific reports - 25 Feb 2020
Kang Hyo Jung, Yoon Sujung, Lee Suji, Choi Koeul, Seol Sihwan, Park Shinwon, Namgung Eun, Kim Tammy D, Chung Yong-An, Kim Jungyoon, Han Jung-Soo, Lyoo In Kyoon
Abstract excerpt
The epigenetic regulation of microRNA (miRNA) expression related to the FK506-binding protein 5 (FKBP5) gene may contribute to the risk of stress-related disorders such as posttraumatic stress disorder (PTSD). Here, we identified candidate miRNAs derived from FKBP5 knockout mice as a potential diagnostic biomarker of PTSD. Using a translational approach, candidate miRNAs found to alter in expression within the...
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