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Article

A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 Sept 2018

Linnstaedt Sarah D, Riker Kyle D, Rueckeis Cathleen A, Kutchko Katrina M, Lackey Lela, McCarthy Kathleen R, Tsai Yi-Hsuan, Parker Joel S, Kurz Michael C, Hendry Phyllis L, Lewandowski Christopher, Datner Elizabeth, Pearson Claire, O'Neil Brian, Domeier Robert, Kaushik Sangeeta, Laederach Alain, McLean Samuel A

Abstract excerpt

Previous studies have shown that common variants of the gene coding for FK506-binding protein 51 (FKBP5), a critical regulator of glucocorticoid sensitivity, affect vulnerability to stress-related disorders. In a previous report, FKBP5 rs1360780 was identified as a functional variant because of its effect on gene methylation. Here we report evidence for a novel functional FKBP5 allele, rs3800373. This study...

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Source

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Identifiers

PMID: 30150364
DOI: 10.1523/JNEUROSCI.3458-17.2018
PMCID: PMC6158694

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain.PMID 30150364Read ↗

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