Article
Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls.
Acta psychiatrica Scandinavica - 1 May 2020
Lyngstad S H, Bettella F, Aminoff S R, Athanasiu L, Andreassen O A, Faerden A, Melle I
Abstract excerpt
OBJECTIVE: Apathy is a central predictor of a poor functional outcome in schizophrenia. Schizophrenia polygenic risk scores (PRSs) are used to detect genetic associations to key clinical phenotypes in schizophrenia. We explored the associations between schizophrenia PRS and apathy levels in schizophrenia spectrum disorders (n = 281) and matched healthy controls (n = 298), and further how schizophrenia PRS...
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