Article
Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients.
Psychopharmacology - 1 Oct 2009
Alkelai Ana, Greenbaum Lior, Rigbi Amihai, Kanyas Kyra, Lerer Bernard
Abstract excerpt
RATIONALE: Antipsychotic-induced parkinsonism (AIP) is a severe adverse affect of neuroleptic treatment. Interindividual heterogeneity in AIP development and severity is associated with risk factors such as antipsychotic drug type, old age, and female gender. There is evidence for genetic predisposition to develop AIP but the variants that confer susceptibility or protection are mostly unknown. OBJECTIVE: To...
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