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Article

A unique feature of swine ANP32A provides susceptibility to avian influenza virus infection in pigs

21 Feb 2020

Abstract excerpt

Both the replication and transcription of the influenza virus are catalyzed by the viral polymerase complex. The polymerases of most avian influenza A viruses have poor performance in mammalian cells, which is considered to be one of the important species barriers. Pigs have been long considered as important intermediate hosts for interspecies transmission of the avian influenza virus, because of their...

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PMID: 32084248
DOI: 10.1371/journal.ppat.1008330

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