Article
Swine ANP32A Supports Avian Influenza Virus Polymerase.
Journal of virology - 1 Jun 2020
Peacock Thomas P, Swann Olivia C, Salvesen Hamish A, Staller Ecco, Leung P Brian, Goldhill Daniel H, Zhou Hongbo, Lillico Simon G, Whitelaw C Bruce A, Long Jason S, Barclay Wendy S
Abstract excerpt
Avian influenza viruses occasionally infect and adapt to mammals, including humans. Swine are often described as "mixing vessels," being susceptible to both avian- and human-origin viruses, which allows the emergence of novel reassortants, such as the precursor to the 2009 H1N1 pandemic. ANP32 proteins are host factors that act as influenza virus polymerase cofactors. In this study, we describe how swine ANP32A,...
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