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Article

Loss of tenomodulin expression is a risk factor for age‐related intervertebral disc degeneration

21 Feb 2020

Abstract excerpt

Abstract The intervertebral disc (IVD) degeneration is thought to be closely related to ingrowth of new blood vessels. However, the impact of anti‐angiogenic factors in the maintenance of IVD avascularity remains unknown. Tenomodulin (Tnmd) is a tendon/ligament‐specific marker and anti‐angiogenic factor with abundant expression in the IVD. It is still unclear whether Tnmd contributes to the maintenance of IVD...

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PMID: 32083813
DOI: 10.1111/acel.13091

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