Article
Differential expression of Tenomodulin and Chondromodulin-1 at the insertion site of the tendon reflects a phenotypic transition of the resident cells.
Tissue & cell - 1 Apr 2010
Yukata K, Matsui Y, Shukunami C, Takimoto A, Hirohashi N, Ohtani O, Kimura T, Hiraki Y, Yasui N
Abstract excerpt
The insertion site of the tendon to the skeletal element is hypovascular and is one of the most common sites of dysfunction in the musculoskeletal system. However, the resident cells have been poorly defined due to a lack of a specific marker for tenocytes. We previously reported that Tenomodulin (Tnmd) and Chondromodulin-1 (Chm1) are homologous angiogenesis inhibitors and predominantly expressed in the avascular...
Topics
- Animals
- Animals, Newborn
- Cartilage
- Chondrocytes
- Cloning, Molecular
- Collagen Type I
- Collagen Type I, alpha 1 Chain
- Collagen Type II
- Connective Tissue Cells
- Erythrocytes
- In Situ Hybridization
- Intercellular Signaling Peptides and Proteins