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Article

Chondromodulin I is dispensable during enchondral ossification and eye development.

Molecular and cellular biology - 1 Sept 2002

Brandau Oliver, Aszódi Attila, Hunziker Ernst B, Neame Peter J, Vestweber Dietmar, Fässler Reinhard

Abstract excerpt

Chondromodulin I (chm-I), a type II transmembrane protein, is highly expressed in the avascular zones of cartilage but is downregulated in the hypertrophic region, which is invaded by blood vessels during enchondral ossification. In vitro and in vivo assays with the purified protein have shown chondrocyte-modulating and angiogenesis-inhibiting functions. To investigate chm-I function in vivo, we generated...

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Identifiers

PMID: 12192060
DOI: 10.1128/MCB.22.18.6627-6635.2002
PMCID: PMC135637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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