Targeted genotyping of circulating tumor DNA for classical Hodgkin lymphoma monitoring: a prospective study.

doi:10.3324/haematol.2019.237719

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Article

Targeted genotyping of circulating tumor DNA for classical Hodgkin lymphoma monitoring: a prospective study.

Haematologica - 1 Jan 2021

Camus Vincent, Viennot Mathieu, Lequesne Justine, Viailly Pierre-Julien, Bohers Elodie, Bessi Lucile, Marcq Bénédicte, Etancelin Pascaline, Dubois Sydney, Picquenot Jean-Michel, Veresezan Elena-Liana, Cornic Marie, Burel Lucie, Loret Justine, Becker Stéphanie, Decazes Pierre, Lenain Pascal, Lepretre Stéphane, Lemasle Emilie, Lanic Hélène, Ménard Anne-Lise, Contentin Nathalie, Tilly Hervé, Stamatoullas Aspasia, Jardin Fabrice

Abstract excerpt

The relevance of circulating tumor DNA (ctDNA) analysis as a liquid biopsy and minimal residual disease tool in the management of classical Hodgkin Lymphoma (cHL) patients was demonstrated in retrospective settings and remains to be confirmed in a prospective setting. We developed a targeted Next-Generation sequencing (NGS) panel for fast analysis (AmpliSeq technology) of nine commonly mutated genes in biopies...

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PMID: 32079702
DOI: 10.3324/haematol.2019.237719
PMCID: PMC7776248

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