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Article

Circulating tumor DNA assisting lymphoma genetic feature profiling and identification.

Annals of hematology - 1 Oct 2024

Wang Hongbiao, Wang Zhao, Zhu Sujuan, Li Zhifeng, Yang Hang, Sun Peng, Zhu Minyi, Zhao Xiaotian, Shen Lu, Ou Qiuxiang, Yang Hui, Li Zhi-Ming

Abstract excerpt

INTRODUCTION: Lymphoma tissue biopsies cannot fully capture genetic features due to accessibility and heterogeneity. We aimed to assess the applicability of circulating tumor DNA (ctDNA) for genomic profiling and disease surveillance in classic Hodgkin lymphoma (cHL), primary mediastinal large B-cell lymphoma (PMBCL), and diffuse large B-cell lymphoma (DLBCL). METHODS: Tumor tissue and/or liquid biopsies of 49...

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Identifiers

PMID: 39012515
DOI: 10.1007/s00277-024-05782-0

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