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Circulating Tumor DNA Assessment in Classic Hodgkin Lymphoma: Ready for Primetime?

Hematology/oncology clinics of North America - 1 Apr 2026

Zamrik Tanja, von Tresckow Bastian, Alig Stefan K

Abstract excerpt

Circulating tumor DNA (ctDNA) has emerged as a promising biomarker in classic Hodgkin lymphoma (cHL). Abundant ctDNA shedding from Hodgkin/Reed-Sternberg cells enables comprehensive molecular profiling directly from plasma. Recent studies have identified mutation- and copy-number-based molecular subtypes which now require harmonization across cohorts. Serial ctDNA monitoring at various landmarks, including end of...

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PMID: 41535187
DOI: 10.1016/j.hoc.2025.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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