Article
Early Posttransplant Mobilization of Monocytic Myeloid-derived Suppressor Cell Correlates With Increase in Soluble Immunosuppressive Factors and Predicts Cancer in Kidney Recipients.
Transplantation - 1 Dec 2020
Utrero-Rico Alberto, Laguna-Goya Rocio, Cano-Romero Francisco, Chivite-Lacaba Marta, Gonzalez-Cuadrado Cecilia, Rodríguez-Sánchez Elena, Ruiz-Hurtado Gema, Serrano Antonio, Fernández-Ruiz Mario, Justo Iago, González Esther, Andrés Amado, Paz-Artal Estela
Abstract excerpt
BACKGROUND: Myeloid-derived suppressor cells (MDSCs) increase in patients with cancer and are associated with poor prognosis; however, their role in transplantation is not yet understood. Here we aimed to study the MDSC effects on the evolution of kidney transplant recipients (KTRs). METHODS: A cohort of 229 KTRs was prospectively analyzed. Two myeloid cells subsets. CD11bCD33CD14CD15HLA-DR (monocytic MDSC...
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