Back to search

Article

Dampened inflammatory signalling and myeloid-derived suppressor-like cell accumulation reduces circulating monocytic HLA-DR density and associates with malignancy risk in long-term renal transplant recipients

2022-03-23

Abstract excerpt

<h4>Background</h4> Malignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating monocytic HLA-DR density is a marker of immune depression in the general population and associates with poorer outcome in critical illness. It has recently been used as a saf...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6666be64-b772-57d0-bb79-53de66f5730e
DOI
10.1101/2022.03.23.22272699
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dampened inflammatory signalling and myeloid-derived suppressor-like cell accumulation reduces circulating monocytic HLA-DR density and associates with malignancy risk in long-term renal transplant recipientsDOI 10.1101/2022.03.23.22272699
Early Posttransplant Mobilization of Monocytic Myeloid-derived Suppressor Cell Correlates With Increase in Soluble Immunosuppressive Factors and Predicts Cancer in Kidney Recipients.Semantic proximity
A shift towards pro-inflammatory CD16+ monocyte subsets with preserved cytokine production potential after kidney transplantation.Semantic proximity
Kidney cancer: Invading immune-cell phenotypes correlate with recurrence risk.Semantic proximity
Clinical and immunological follow-up of very long-term kidney transplant recipients treated with calcineurin inhibitors indicates dual phenotypes.Semantic proximity
Peripheral transcriptomic signature of chronic antibody-mediated rejection in kidney transplantation: a dual effect for <i>MMP9</i> over timeSemantic proximity
CLINICOPATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF PLASMA CELL RICH REJECTION IN RENAL TRANSPLANT BIOPSIESSemantic proximity
Changes in phenotypic patterns of blood monocytes after kidney transplantation and during acute rejection.Semantic proximity
Impaired Secretion of TNF-α by Monocytes Stimulated With EBV Peptides Associates With Infectious Complications After Kidney Transplantation.Semantic proximity
Intratumoral CD14+ Cells and Circulating CD14+HLA-DRlo/neg Monocytes Correlate with Decreased Survival in Patients with Clear Cell Renal Cell Carcinoma.Semantic proximity
Circulating Monocytic Myeloid‐Derived Suppressor Cells Are Elevated and Associated with Poor Prognosis in Acute Myeloid LeukemiaSemantic proximity
Molecular diagnostics identifies risks for graft dysfunction despite borderline histologic changes.Semantic proximity
DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiationSemantic proximity
Select a neighboring publication to make it the new centre.