Article
Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study.
Diabetes care - 1 Apr 2020
Emanuelsson Frida, Marott Sarah, Tybjærg-Hansen Anne, Nordestgaard Børge G, Benn Marianne
Abstract excerpt
OBJECTIVE: To evaluate whether high glucose levels in the normoglycemic range and higher have a causal genetic effect on risk of retinopathy, neuropathy, nephropathy, chronic kidney disease (CKD), peripheral arterial disease (PAD), and myocardial infarction (MI; positive control) in the general population. RESEARCH DESIGN AND METHODS: This study applied observational and one-sample Mendelian randomization (MR)...
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