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Mendelian randomization analysis reveals causal factors behind diabetic nephropathy: evidence, opportunities, and challenges.

Frontiers in endocrinology - 1 Jan 2024

Huang Qinchuan, An Chen, Tang Shiyun, Leng Yulin, Zhang Yaowen, Wan Bin, Han Yutong, Luo Yue, Xie Chunguang

Abstract excerpt

Diabetic nephropathy (DN), as the most serious minor vascular complication of diabetes, imposes a significant socioeconomic and medical cost around the world, and its prevention and treatment are a major challenge in the current medical community. Observational studies and randomized controlled trials have revealed protective and risk factors for some DN. However, the conclusions of these researches may be...

Topics

Humans
Mendelian Randomization Analysis
Diabetic Nephropathies
Risk Factors
Genetic Predisposition to Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39735650
DOI: 10.3389/fendo.2024.1444808
PMCID: PMC11671268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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