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Article

High throughput sequencing reveals the diversity of TRB-CDR3 repertoire in patients with psoriasis vulgaris.

International immunopharmacology - 1 Nov 2016

Cao Xiaofang, Wa Qingbiao, Wang Qidi, Li Lin, Liu Xin, An Lisha, Cai Ruikun, Du Meng, Qiu Yue, Han Jian, Wang Chunlin, Wang Xingyu, Guo Changlong, Lu Yonghong, Ma Xu

Abstract excerpt

Psoriasis is a T cell-mediated chronic inflammatory skin disease with inflammatory cell infiltrates in the dermis and epidermis. Previous studies suggested that there are some expanded T-cell receptor (TCR) clones in psoriatic skin. However, the effect of psoriasis on the immunological characteristics of TCR in circulating blood has not been reported. To address this, we performed high-throughput sequencing to...

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Share to Complementarity Determining Regions
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27743555
DOI: 10.1016/j.intimp.2016.10.004

Genes

TRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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