Exomic sequencing of immune-related genes reveals novel candidate variants associated with alopecia universalis.

Abstract excerpt

Alopecia areata (AA) is a common autoimmune disorder mostly presented as round patches of hair loss and subclassified into alopecia totalis/alopecia universalis (AT/AU) based on the area of alopecia. Although AA is relatively common, only 5% of AA patients progress to AT/AU, which affect the whole scalp and whole body respectively. To determine genetic determinants of this orphan disease, we undertook whole-exome...

Topics

Join the communities discussing this publication.

• Alopecia
• Child, Preschool
• Exome
• Genetic Association Studies
• Genetic Markers