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Article

Identification of prognostic genes in the acute myeloid leukemia microenvironment

18 Nov 2019

Abstract excerpt

The tumor microenvironment (TME) has a strong influence on the progression, therapeutic response, and clinical outcome of acute myeloid leukemia (AML), one of the most common hematopoietic malignancies in adults. In this study, we identified TME-related genes associated with AML prognosis. Gene expression profiles from AML patients were downloaded from TCGA database, and immune and stromal scores were calculated...

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PMID: 31740623
DOI: 10.18632/aging.102477

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