Poor prognosis associated with TERT gene alterations in meningioma is independent of the WHO classification: an individual patient data meta-analysis.

doi:10.1136/jnnp-2019-322257

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Poor prognosis associated with TERT gene alterations in meningioma is independent of the WHO classification: an individual patient data meta-analysis.

Journal of neurology, neurosurgery, and psychiatry - 1 Apr 2020

Mirian Christian, Duun-Henriksen Anne Katrine, Juratli Tareq, Sahm Felix, Spiegl-Kreinecker Sabine, Peyre Matthieu, Biczok Annamaria, Tonn Jörg-Christian, Goutagny Stéphane, Bertero Luca, Maier Andrea Daniela, Møller Pedersen Maria, Law Ian, Broholm Helle, Cahill Daniel P, Brastianos Priscilla, Poulsgaard Lars, Fugleholm Kåre, Ziebell Morten, Munch Tina, Mathiesen Tiit

Abstract excerpt

BACKGROUND: TERT gene alterations (TERT-alt) have been linked to increased risk of recurrence in meningiomas, whereas the association to mortality largely remain incompletely investigated. As incongruence between clinical course and WHO grade exists, reliable biomarkers have been sought. METHODS: We applied the Preferred Reporting Items for Systematic Review and Meta-Analyses of individual participant data...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Meningeal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Meningioma

Share to Mutation

Share to Prognosis

Share to Promoter Regions, Genetic

Share to Survival Rate

Share to Telomerase

Share to World Health Organization

Source

Open in PubMed

Identifiers

PMID: 32041819
DOI: 10.1136/jnnp-2019-322257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Poor prognosis associated with TERT gene alterations in meningioma is independent of the WHO classification: an individual patient data meta-analysis.PMID 32041819Read ↗

TERT promoter mutations in primary and secondary WHO grade III meningiomaSemantic proximity Read ↗

Implementation of TERT promoter mutations improve prognostication of the WHO classification in meningioma.Semantic proximity Read ↗

High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression.Semantic proximity Read ↗

The effect of TERT promoter mutation on predicting meningioma outcomes: a multi-institutional cohort analysis.Semantic proximity Read ↗

TERT Promoter Mutations and Risk of Recurrence in Meningioma.Semantic proximity Read ↗

TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.Semantic proximity Read ↗

Classification based on mutations of TERT promoter and IDH characterizes subtypes in grade II/III gliomas.Semantic proximity Read ↗

Predictors of early recurrence in meningiomaSemantic proximity Read ↗

TERT promoter mutation and its interaction with IDH mutations in glioma: Combined TERT promoter and IDH mutations stratifies lower-grade glioma into distinct survival subgroups-A meta-analysis of aggregate data.Semantic proximity Read ↗

TERT promoter mutations are associated with poor prognosis and cell immortalization in meningioma.Semantic proximity Read ↗

Grade-Specific Influences of MGMT and TERT Genes on the Prognosis of GliomaSemantic proximity Read ↗

Progression-Free Survival and Molecular Features of Recurrent Intracranial Meningiomas: A Single-Center Retrospective StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.