Article
TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.
Journal of neuro-oncology - 1 Sept 2018
Biczok Annamaria, Kraus Theo, Suchorska Bogdana, Terpolilli Nicole A, Thorsteinsdottir Jun, Giese Armin, Tonn Joerg C, Schichor Christian
Abstract excerpt
INTRODUCTION: Transcriptional activating mutations in the promoter region of the telomerase reverse transcriptase (TERT) gene occur at high frequency in various types of solid tumors and have also been reported for meningiomas. Especially for atypical and anaplastic meningiomas, the prognostic relevance of TERT promoter mutation is yet unclear. The present study aimed to analyze the frequency of TERT promoter...
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