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Article

Polygenic Risk Score-Derived Subcortical Connectivity Mediates Attention-Deficit/Hyperactivity Disorder Diagnosis.

Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Mar 2020

Hermosillo Robert J M, Mooney Michael A, Fezcko Eric, Earl Eric, Marr Mollie, Sturgeon Darrick, Perrone Anders, Dominguez Oscar Miranda, Faraone Stephen V, Wilmot Beth, Nigg Joel T, Fair Damien A

Abstract excerpt

BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) has substantial heritability, and a recent large-scale investigation has identified common genome-wide significant loci associated with increased risk for ADHD. Along the same lines, many studies using noninvasive neuroimaging have identified differences in brain functional connectivity in children with ADHD. We attempted to bridge these studies to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32033925
DOI: 10.1016/j.bpsc.2019.11.014
PMCID: PMC7147985

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