Shared intrinsic functional connectivity alterations as a familial risk marker for ADHD: a resting-state functional magnetic resonance imaging study with sibling design.

Abstract excerpt

BACKGROUND: Although aberrant intrinsic functional connectivity has been reported in attention-deficit/hyperactivity disorder (ADHD), we have a limited understanding of whether connectivity alterations are related to the familial risk of ADHD. METHODS: Fifty-three probands with ADHD, their unaffected siblings (n = 53) and typically developing controls (n = 53) underwent resting-state functional magnetic resonance...

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