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Article

Genetic Etiology Link to Brain Function Underlying ADHD Symptoms and its Interaction with Sleep Disturbance: An ABCD Study.

Neuroscience bulletin - 1 Jun 2025

Feng Aichen, Zhi Dongmei, Fu Zening, Yu Shan, Luo Na, Calhoun Vince, Sui Jing

Abstract excerpt

Attention deficit hyperactivity disorder (ADHD), a prevalent neurodevelopmental disorder influenced by both genetic and environmental factors, remains poorly understood regarding how its polygenic risk score (PRS) impacts functional networks and symptomology. This study capitalized on data from 11,430 children in the Adolescent Brain Cognitive Development study to explore the interplay between PRSADHD, brain...

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Identifiers

PMID: 39827443
DOI: 10.1007/s12264-025-01349-9
PMCID: PMC12158910

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