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Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder

30 Nov 2023

Abstract excerpt

Attention deficit hyperactivity disorder (ADHD) is a complex disorder that manifests variability in long-term outcomes and clinical presentations. The genetic contributions to such heterogeneity are not well understood. Here we show several genetic links to clinical heterogeneity in ADHD in a case-only study of 14,084 diagnosed individuals. First, we identify one genome-wide significant locus by comparing cases...

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PMID: 38036780
DOI: 10.1038/s41588-023-01593-7

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