Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic risk for five psychiatric disorders and cross-disorder and disorder-specific neural connectivity in two independent populations.

NeuroImage. Clinical - 1 Jan 2017

Wang Tianqi, Zhang Xiaolong, Li Ang, Zhu Meifang, Liu Shu, Qin Wen, Li Jin, Yu Chunshui, Jiang Tianzi, Liu Bing

Abstract excerpt

Major psychiatric disorders, including attention deficit hyperactivity disorder (ADHD), autism (AUT), bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SZ), are highly heritable and polygenic. Evidence suggests that these five disorders have both shared and distinct genetic risks and neural connectivity abnormalities. To measure aggregate genetic risks, the polygenic risk score (PGRS) was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Disorder with Hyperactivity
Share to Autistic Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Mapping

Share to Datasets as Topic

Share to Depressive Disorder, Major

Share to Image Processing, Computer-Assisted

Share to Mental Disorders

Share to Psychiatric Status Rating Scales

Source

Open in PubMed Open full text

Identifiers

PMID: 28275544
DOI: 10.1016/j.nicl.2017.02.011
PMCID: PMC5328751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic risk for five psychiatric disorders and cross-disorder and disorder-specific neural connectivity in two independent populations.PMID 28275544Read ↗

Cross-Disorder Analysis of Shared Genetic Components Between Cortical Structures and Major Psychiatric Disorders.Semantic proximity Read ↗

[New directions in psychiatric genetics: Genome-wide association studies, polygenic risk score and cross-disorder analysis].Semantic proximity Read ↗

Associated Genetics and Connectomic Circuitry in Schizophrenia and Bipolar Disorder.Semantic proximity Read ↗

Genetic overlap between multivariate measures of human functional brain connectivity and psychiatric disordersSemantic proximity Read ↗

The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysisSemantic proximity Read ↗

A structural brain network of genetic vulnerability to psychiatric illness.Semantic proximity Read ↗

Shared genetic architecture across psychiatric disorders.Semantic proximity Read ↗

Associated genetics and connectomic circuitry in schizophrenia and bipolar disorderSemantic proximity Read ↗

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.Semantic proximity Read ↗

The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences.Semantic proximity Read ↗

Polygenic risk score for five major psychiatric disorders associated with volume of distinct brain regions in the general population.Semantic proximity Read ↗

Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.